Vitamin B12 shot side effects Most people tolerate vitamin B12 injections well, but possible side effects include: Mild: soreness or redness at injection site, mild diarrhea, nausea, headache, itching Rare but serious: allergic reactions (rash, swelling, difficulty breathing), low potassium (hypokalemia), dizziness or heart rate changes Get emergency medical help if you have signs of an allergic reaction to Vitamin B12: hives
Rare but Serious Complications Even though rare, serious problems can happen with Vitamin B12 shots
Studies comparing routes consistently show IV glutathione produces five to ten times higher peak plasma concentrations than oral dosing (PubMed PMID: 24791752)
Huang, P., Deng, H., Zhou, Y