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The extrinsic pathway is initiated by the binding of extracellular death ligandsincluding Fas ligand (FasL), tumor necrosis factor (TNF)-, and TNF-related apoptosis-inducing ligand (TRAIL)to their corresponding death receptors such as Fas receptor (FasR), tumor necrosis factor receptor 1 (TNFR1), death receptor 4 (DR4), and death receptor 5 (DR5) [9, 29]
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J Clin Neurosci (2020) 81:2349
