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Participants were also advised to follow a reduced-calorie diet and increased physical activity , so the results reflect medication plus lifestyle changes, not tirzepatide alone
The peptide that semaglutide mimics targets the areas in the brain that regulate appetite and food intake
Effect of tirzepatide versus insulin degludec on liver fat content and abdominal adipose tissue in people with type 2 diabetes (SURPASS-3 MRI): a substudy of the randomised, open-label, parallel-group, phase 3 SURPASS-3 trial
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