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PT-141 (Bremelanotido) es un heptapptido cclico sinttico derivado de Melanotan II, pero con especificidad mejorada para el receptor melanocortina 4 (MC4R) y actividad reducida sobre MC1R (lo que reduce los efectos de pigmentacin)
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doi: 10.1016/S2468-1253(19)30089-5 92 GuoX.SuY.DuY.ZhangF.YuW.RenW.et al
Retatrutide for type 2 diabetes: Phase 2 trial results (36-week study, HbA1c reductions, weight loss) New England Journal of Medicine (2023) Jastreboff AM, et al
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