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Similar content being viewed by others Introduction Glucagon-like peptide-1 (GLP-1), encoded as a fragment of proglucagon in the preproglucagon gene ( Gcg ), is expressed in the brain, pancreatic alpha cells and enteroendocrine cells within the intestine
Clinical trials, such as STEP 1, have shown that semaglutide can help patients lose nearly 15% of their body weight, significantly more than the placebo group
The difference is that they often do so at greater concentrations, for longer durations, or with more sustained receptor activation than would normally occur
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