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One important note: this isnt necessarily a more is better situation
If you take both metformin and tirzepatide, your risk of B12 deficiency is compounded (no pun intended)
Mechanistically, it acts as a ghrelin mimetic, binding the growth hormone secretagogue receptor (GHS-R1a) the receptor for the endogenous peptide ghrelin, expressed in the pituitary and hypothalamus
Continue Reading Do B12 injections expire
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