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However, one study on the treatment of children with methylmalonic acidemia and homocystinuria found oral hydroxocobalamine at 1 mg daily to be ineffective in reducing levels of homocysteine
Botta D, Franklin CC, White CC, Krejsa CM, Dabrowski MJ, Pierce RH et al
ePA itself does not necessarily change coverage rules
Timing Options: Upon waking: 30-60 minutes before breakfast Before bed: 2-3 hours after last meal Split dosing: Morning and evening for higher doses Consistency in timing helps maintain stable peptide levels and allows for better tracking of response patterns
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