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10.1001/jamanetworkopen.2019.0905 JAMA Netw Open

Peptides sprayed into the nose bypass the digestive system entirely, avoiding the enzymatic degradation that destroys oral peptides

Under federal law, compounded medications may be prepared by state-licensed pharmacies for individual patients whose needs cannot be met by approved products or, in limited circumstances, while a product is on the FDA's shortage listsubject to strict conditions under Section 503A and 503B of the Federal Food, Drug, and Cosmetic Act