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He won an Olivier award for The Book of Mormon
Patients who report constipation starting in weeks 1-4 fall into two groups by week 6: Group 1 (adapters, ~65% of those with early constipation): Bowel movement frequency has stabilized or started improving by week 6
As a result, the half-life was extended to 1516 days (compared to the one-week duration of analogs like semaglutide or tirzepatide) while maintaining equivalent potency, opening the door for once-monthly instead of weekly administration
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