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For those participating in a clinical trial, all adverse effects even those that seem minor should be reported to the trial team as part of the pharmacovigilance process

The results showed that tirzepatide promoted HbA1c reductions of between 1.8% and 2.4%, and body weight losses of up to 20.9%, being superior to other incretin-based therapies, such as semaglutide and liraglutide

2006, pp

And rarely, patients using Ozempic may experience more severe side effects such as: Allergic reactions (including hives, swelling, and difficulty breathing) Pancreatitis (inflammation of the pancreas) Kidney problems If you experience any of these side effects, it's important to stop taking Ozempic and consult with your doctor immediately