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High fat diet treatment reduces adiponectin level in mice, which has been suggested as a mechanism underlying diet-induced insulin resistance and diabetes [12, 13]
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The increased levels of norepinephrine, dopamine, and serotonin in the hypothalamus, specifically in the arcuate nucleus, lead to the activation of neurons that express pro-opiomelanocortin (POMC) and cocaine- and amphetamine-regulated transcript (CART)
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