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It is approved for extended adjuvant therapy in HER2-positive breast cancer as a single agent and in combination with capecitabine for advanced or metastatic disease (Geyer et al., 2006
Note the shot or pill day and any dose change, so symptom timing can be compared against it
Those with active pancreatitis or a history of severe GI motility issues (since these medications slow digestion)
doi:10.1007/s00114-016-1362-3
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