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GLP-1 therapies influence pathways tied to addiction and reward, according to the Endocrine Society A randomized clinical trial published in JAMA Psychiatry found semaglutide reduced alcohol cravings and consumption Users commonly report: Reduced desire to drink Feeling full faster when drinking Less reward from alcohol The data: early, but directionally consistent While long-term industry sales data is still developing, the early signals from clinical studies, observational research, and population polling all point in the same direction: GLP-1 use is associated with lower alcohol consumption for at least some users

(PubMed) Choi HK, Gao X, Curhan G

J Ocul Pharm Ther 2023;39:66171

doi: 10.1038/s41423-024-01232-z 77 HaoZ-NTanX-PZhangQLiJXiaRMaZ