Mitchell JL, Lyons HS, Walker JK, Yiangou A, Grech O, Alimajstorovic Z, Greig NH, Li Y, Tsermoulas G, Brock K, Mollan SP, Sinclair AJ (2023) The effect of GLP-1RA exenatide on idiopathic intracranial hypertension: a randomized clinical trial
The reduction was relatively selective for visceral adipose tissue the metabolically active fat packed around the abdominal organs while subcutaneous fat was not reduced to a clinically significant extent
In addition, it modulates the glutamatergic pathway and possesses anti-neurotic and antioxidant properties
Retatrutide is the lead triple agonist, hitting GLP-1, GIP, and glucagon receptors at once