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How Treatment Overcomes the Defect For many genetic disorders, treatments only manage symptoms
Think about what that means: You can choose a drug known to cause liver damage But you can't choose a peptide whose risks are simply unstudied A patient can accept documented risk of organ failure
You can read the abstract at Semaglutide 24 mg once a week in adults with overweight or obesity, and type 2 diabetes (STEP 2): a randomised, double-blind, double-dummy, placebo-controlled, phase 3 trial A group of researchers conducted a phase 3 clinical trial to examine the efficacy and safety of subcutaneous semaglutide 2.4 mg once per week, semaglutide 1.0 mg (licensed for the treatment of diabetes), and placebo in managing weight in an adult population who were overweight or obese and have type 2 diabetes
Under ad libitum feeding conditions, we found that heart, body, and heart/body weights and nonfasting tail blood glucose measurements were not affected by treatment assignment (Supplemental Figure 1
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