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Early deregulation of miRNAs such as miR-187-3p, miR-182-5p, and miR-34c-5p has been observed in human-induced pluripotent stem cell-derived cardiomyocytes exposed to doxorubicin, suggesting their potential as early cardiotoxicity biomarkers
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It is also known that oral contraceptives may lower pyridoxine levels in some individuals, which could be considered a drug-nutrient interaction of clinical relevance
