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Patients with a history of pancreatitis face substantially higher recurrence risk and should discuss alternative treatments with their healthcare provider, as FDA labeling advises considering other therapies in this population

However, there are differences in dosing, side effects, and cost that may influence the decision-making process when choosing between the two

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Therefore, future research should explore the interplay among various PCD pathways, identify key molecular nodes, and leverage multi-omics technologies to construct a comprehensive PCD regulatory network associated with DOR