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doi:10.1152/physrev.1998.78.2.393
The peptide's efficacy against high-SASP senescent cells proves particularly valuable in the kidney microenvironment, where inflammatory signaling from senescent tubular cells impairs filtration and promotes fibrosis
Inverse salt sensitivity results in part from genetic polymorphisms in various Na + regulatory genes leading to a decrease in natriuretic activity and an increase in renal tubular Na + reabsorption leading to an increase in BP
doi: 10.3390/nu15153375 Pascolini D, Mariotti SP
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