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typical oral doses range 250500 mg daily, though some protocols use up to 1,000 mg divided doses
The SELECT trial result - 20% reduction in major cardiovascular events with weekly semaglutide 2.4mg in adults with established cardiovascular disease plus overweight/obesity - was the first time a weight-loss medication demonstrated cardiovascular outcome benefits in a major randomized controlled trial
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PREVENT-HF: Primary and secondary prevention of heart failure in high-risk obese patients with GLP-1RA led by Varun Sundaram, M.D., Ph.D., associate professor at Case Western Reserve University School of Medicine
