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Many have advocated that the associations between low mood, suicidal behavior and anti-obesity drugs such as GLP-1RAs are confounded by the pre-existing higher prevalence of neuropsychiatric disorders observed in people living with obesity compared with the general population 236

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We have shown the difference between VRK2-WT cells and VRK2-KO cells in the sensitivity to GSH inhibition and noted that sensitive cells exhibited surged ROS levels following GSH inhibition (Fig