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TISSUE-SPECIFIC FEATURES OF GLUTATHIONE IMPORT TO MITOCHONDRIA Previous studies in a renal proximal tubular cell line, NRK-52E, indicated that overexpression of OGC and DIC increased mGSH levels and protected against oxidant-mediated cell death (Xu et al., 2006)

Studies have shown that autistic children exhibit lower levels of plasma-reduced glutathione, with levels generally 2040% lower compared to typically developing children