Elbini Dhouib I, Jallouli M, Annabi A, Gharbi N, Elfazaa S, Lasram MM
Platelet Delivery System: T4 is ubiquitously expressed in cells and extracellular fluids, is released by platelets upon activation, and its concentration increases at sites of injury a distribution pattern that delivers the peptide directly into forming wounds (PMID 22944663)
Most of the longevity data comes from animal studies, laboratory models, or small observational research from a limited group of investigators
on the other hand, ROS explosion and the spread of inflammatory signals further enhance necroptosis and pyroptosis, and in some cases, affect autophagic function