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This approach significantly suppresses tissue damage caused by OxS in T2DM patients [38]

Gastrointestinal side effects include: Nausea (15-30% of patients depending on dose): Usually mild to moderate and decreasing over time Diarrhea (13-24%): May contribute to dehydration if persistent Vomiting (6-12%): More common at higher doses Constipation (5-17%): Can alternate with diarrhea in some patients Abdominal pain (6-10%): Typically mild and self-limiting Decreased appetite : An intended effect contributing to weight loss Hypoglycemia risk varies depending on concurrent medications

AMH decreases with age until it becomes essentially undetectable around menopause

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