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This principle was also explored by scientists at Affibody, who showed that the alternative molecular scaffold of affibodies could be expressed as a fusion protein with an albumin-binding domain and used to prevent IgG binding to FcRn both in vitro and in WT mice (i.e., mice expressing native mouse FcRn) [125]
Besides affecting lipid metabolism, the peptide is being studied for its potential use in tissue engineering, wound healing, and cartilage repair
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Jun 2017;95(6):1257-1270
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