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Several GLP-1 receptor agonists have demonstrated cardiovascular benefits in specific populations, with varying magnitudes of risk reduction for major adverse cardiovascular events in landmark trials

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The FDA gave the green light to semaglutide (under the brand name Wegovy) in June of 2021 for weight management for adults with obesity or overweight accompanied by at least one weight-related condition, such as elevated blood pressure, type 2 diabetes, or high cholesterol