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A landmark study examined electronic health records from multiple healthcare systems and identified a statistically significant elevation in the incidence of nonarteritic anterior ischemic optic neuropathy among patients prescribed these medications compared to those receiving alternative diabetes or weight management therapies

95% CI, 0.46-0.76) and CV death (HR = 0.55

The prognosis for mucosal melanoma is worse than for cutaneous melanoma, suggesting that patients require more aggressive treatment [3, 4]

Higher doses of retatrutide reduced biomarkers of insulin resistance, including fasting insulin, fasting C-peptide and HOMA2-IR, by up to 50% or more from baseline