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A 2024 study in Brain, Behavior, & Immunity - Health identified severe CD8 T-cell dysfunction in both ME/CFS and Long COVID patients, linking this immune exhaustion directly to mitochondrial failure

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Synthesis of ROS-sensitive polymers (P3) To a solution of ROS sensitive compound (2,2-(propane-2,2-diylbis(sulfanediyl))bis(ehan-1-ol)) (0.26 g, 1.35 mmol) in anhydrous DMF (5 ml), 1,2,4,5-cyclohexanetetracarboxylic dianhydride (0.31 g, 1.41 mmol) was quickly added into the solution