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In this experiment, arterial blood gas results indicated different degrees of hypoxia in groups B, C and D animals housed in a hypobaric hypoxic animal chamber: decreased PO 2 , increased PCO 2 , increased Hb or HCT, and elevated K + and Cl levels
Figure 9 3.8 Proposed substrate recognition and enzyme mechanism of MSA-DH The potential substrate binding site of MSA-DH was explored by superimposing the three-dimensional structure of human succinic semialdehyde dehydrogenase in complex with its substrate (PDB ID: 2W8Q) (Supplementary Figure S1)
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