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Humans express six large families of methyltransferases identified as the homocysteine methyltransferase family, the lysine methyltransferase family, the radical S -adenosylmethionine domain containing family, the seven-beta-strand methyltransferase motif containing family, the SET domain containing family, and the SPOUT methyltransferase domain containing family

Studies showed that the decrease of Nrf2 down-regulated GPX4, depleted GSH and caused the ferroptosis in HSV-1 infected cells (Xu et al., 2023)

18, 254259.10.1094/MPMI-18-0254 10 FrendoP.JimnezM