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Microenvironment-responsive phototherapeutic platforms that sense biochemical cues including redox status allow activation only within pathological niches, improving safety and enabling synergistic combinations with GSH-consuming or GSH-responsive agents to bias tumor redox balance toward therapeutic ROS generation [21]
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Peptides from the mitochondrial-IP were separated across a 90-minute linear gradient and peptides from the whole-cell lysate were separated across a 120-minute linear gradient going from 7 to 33% B solvent at 300nL/minute
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