10.1016/j.cardiores.2006.02.025 Summary Keywords ferroptosis inhibitors, flavonoids, natural compounds, central nervous system diseases, molecular mechanisms Citation Li Q, Yang X and Li T (2025) Natural flavonoids from herbs and nutraceuticals as ferroptosis inhibitors in central nervous system diseases: current preclinical evidence and future perspectives
2) Dihexa was shown to improve cognitive impairments and recover memory by inhibiting inflammation and decreasing neuronal loss by affecting the PI3K/AKT signaling pathways
In this view, nutrients, such as glucose or free fatty acids, provide intermediate metabolites the ability to interact directly with an enzyme (the metabolic sensor) that rules the rate limiting step of a metabolic process, thus regulating substrate preference
Reported cell-culture systems include dermal fibroblast and keratinocyte monolayers, where the tripeptide is studied in the context of collagen and glycosaminoglycan turnover
