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The New England Journal of Medicine, 389 (24), 22212232
Maternal polymorphisms of folate pathway genes and risk of congenital heart defects in the DS child Several congenital complications are observed in individuals with DS (for a review see Weijerman and de Winter, 2010), some of which potentially affected by impaired maternal one-carbon metabolism and consequent epigenetic changes during embryogenesis or impaired requirements of DNA precursors for cellular divisions
Additionally, combining reduction and derivatization steps helps to reduce the number of polypropylene tubes and plastic laboratory waste
It also slows down gastric emptying, which helps to regulate appetite by making people feel fuller for longer
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