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Results Tirzepatide alleviated the blood lipid profile and liver damage in the HFD-induced MAFLD model To evaluate the efficacy of establishing a mouse model of fatty liver, we recorded the weekly weight changes of the mice as an indicator of model success

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But the drug will need to be tested in much bigger trials to assess its effects in larger groups of people

Researchers can then use receptor-selective blocking methods, genetic changes, or other validated approaches to test how much each receptor contributes to the measured response