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This narrative mini-review aims to describe the involvement of the GH/IGF-1/IGF-1R axis in either mediating or responding to the effects of each of the two drug classes

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As a GLP-1 receptor agonist, Ozempic is frequently used to help people with type 2 diabetes control their blood sugar levels

At the cellular level, under hypoxic conditions, the hypoxiainducible factor (HIF)prolyl hydroxylase family of enzymes (PHD13) lose their ability to hydroxylate HIF because they rely on O 2 for their enzymatic activity [139]