dpp 4 inhibitors with glp 1 GLP-1-RA and DPP-4 in the management of type 2 diabetes Design principles of long-acting DPP-4

Figure 3 Metabolic effects Bodyweight reduction GLP-1 has a documented dose-dependent effect on satiety, through central mechanisms in the hypothalamus and brainstem

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[8] In such patients, MB should be avoided or used only with close monitoring, and at minimum, dosage reduction is advised