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It increases the accessibility of such drugs, promotes compliance, and results in improved patient outcomes

Gold: Nitritoid reactions (symptoms include facial flushing, nausea, vomiting and hypotension) have been reported rarely in patients on therapy with injectable gold (sodium aurothiomalate) and concomitant ACE inhibitor therapy including captopril and hydrochlorothiazide tablets

Metabolic adaptation occurs in some individuals, where the body adjusts to reduced caloric intake by decreasing metabolic rate

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