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While tirzepatide's primary therapeutic targets relate to metabolic function, receptor activation in these brain areas could potentially influence mood pathways, though human evidence for direct effects remains limited and inconclusive

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After 1 year of this treatment, a cessation of further gain was observed for the first time, with BMI decreasing to 50.3 kg/m 2 - a level that remained elevated but suggested a halt in disease progression

During maintenance, once you have reached your target dose and your weight loss has stabilized, timing flexibility increases