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Maintaining iron homeostasis is critical for immune competence, red blood cell production, metabolic regulation, and the control of cell growth ( Tfrc is predominantly expressed in brown adipocytes and has been implicated in regulating BAT development and thermogenic activation, possibly through iron-mediated metabolic pathways

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All the parameters of LV measurement were showed in Supplementary Table 1

The findings show that with respect to sleep-wake pattern, sleep duration, and daytime activity the two schedules were comparable, and all patients slept well within the normal pediatric range