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To identify potential PAR2-activating proteases expressed in the gut, we performed single-cell RNA sequencing of intestinal crypt cells and identified subpopulations by distinct marker transcripts (Figure 1A and Supplemental Figure 1A

These medicines had significant effects on gastrointestinal emptying and postprandial glucose regulation, but these effects were restricted to meals consumed quickly after administration (Nauck and Meier 2019)

[PMID: 25779601] PubMed record related to this compound for laboratory literature review

This recommendation is particularly relevant for individuals who were sedentary before starting tirzepatide and feel motivated to exercise due to increased energy