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Second-generation TKIs Dasatinib, nilotinib, ponatinib, and bosutinib are second-generation TKIs that are used for treatment of Ph+CML

More subcutaneous fat means a longer needle is needed to reach muscle reliably

In 1986, a group of doctors wrote in an article: This group (of 41 chronically ill patients) had somatization disorder diagnosed by specific criteria

This broader effect is one reason its drawn interest from people managing chronic inflammatory conditions not just localized injuries
