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This is more common in the lower extremities due to fluid retention and other changes
Extended telogen and shortened anagen contribute to thinning over time
It increases VEGF receptor activity to promote new blood vessel formation, enhances collagen synthesis and organization, activates the ERK1/2 signaling pathway for cell proliferation and migration, and modulates inflammatory responses to optimize healing conditions
in accordance with the principles outlined in the Guide to the Care and Use of Experimental Animals as published by the Canadian Council on Animal Care and the NIHs Guide for the Care and Use of Laboratory Animals
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