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Optimal thyroid hormone replacement remains the foundation of treatment, but additional strategies may be appropriate for select patients who continue to experience weight-related challenges despite adequate thyroid management

Fat-free mass increased by 1.1 kg, while the placebo group lost 0.5 kg (Nass et al., Annals of Internal Medicine , 2008)

Both produce weight loss that includes a proportion of lean mass alongside fat typically 2040% of total weight lost is lean tissue in trials without structured exercise

A review on gut remediation of selected environmental contaminants: possible roles of probiotics and gut microbiota