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Conclusion: GLP-1based therapies are associated with predictable GI adverse effects, most of which are mild to moderate and manageable
While it can slightly increase hydration in tissues, it does not lead to fat or water weight gain
The development of drug resistance is a challenge for the use of adjuvant therapies in breast cancer patients [69], and studies suggest that ROS may play an important role in the production of drug-resistant cells [70]
The cell-surface-selective activity may result from Golgi localization of copper chaperones and greater oxygen availability at the cell surface
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