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Some early studies have suggested GLP-1s can tamp down the drug-related cravings of people with substance use disorders, for instance
Some patients feel encouraged and lighter as weight begins to come off
Renal function has minimal impact on tirzepatide clearance, as the medication is primarily metabolized through proteolytic pathways rather than renal excretion
Other conditions common in people with obesity or diabetes can also contribute to fatigue, including sleep apnoea, thyroid disorders, and depression
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