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Proc Natl Acad Sci U S A 92:1131211316 Ellouzi H, Hamed KB, Hernndez I, Cela J, Mller M, Magn C, Abdelly C, Munn-Bosch S (2014) A comparative study of the early osmotic, ionic, redox and hormonal signalling response in leaves and roots of two halophytes and a glycophyte to salinity

Clinical trials targeting signaling pathways Targeting the PI3K/AKT pathway The PI3K/AKT pathway is regarded as a common oncogenic signaling pathway

Multiple organ failure including sepsis-induced cardiac dysfunction seem to be the result of numerous factors as overwhelming inflammation and nitric oxide synthesis impairment associated with mitochondrial dysfunction and increased oxidative stress (Cecchini and Cecchini, 2020)

Lok, A., Bockting, C