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Interestingly, the results indicated that GSH concentrations in plasma showed a more significant increase and a higher rate (Cmax) and extent of absorption (AUC0-t) following S-Acetyl-L-glutathione administration compared to the reference GSH product

Similarly, recruitment of participants with severe hepatic impairment into the hepatic impairment study was challenging and, despite a third study site being added and the recruitment period being prolonged, it was not possible to complete recruitment of seven participants into the severe hepatic impairment group

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