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Potential side effects of Semaglutide GLP-1, such as nausea, vomiting, and diarrhea due to appetite suppression and slower gastric emptying, could be more pronounced in individuals with a lower BMI
Additionally, it decreases inflammation by reducing pro-inflammatory cytokines and increasing anti-inflammatory ones, thereby improving insulin sensitivity and decreasing tissue inflammation [41, 233]
SGLT2 inhibitors would have a slight preference in the setting of CKD, but those patients also should be on both SGLT2 inhibitors and GLP-1 receptor agonists independent of glucose control, McGuire told TCTMD
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