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[3] [8] Patients taking oral mesalamine, immunosuppressants, or other time-sensitive medications should discuss optimal timing and monitoring

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Several alternative therapeutic strategies have been investigated, including protein kinase C inhibitors [10], darbepoetin alfa [11], endothelin receptor antagonists (ERAs) [12], direct renin inhibitors [13], nuclear factor erythroid 2-related factor 2 activators [14], and combination of ACE inhibitor and ARB [15]

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