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There is no strong evidence that Ozempic (semaglutide) directly causes missed periods that came out of the clinical trials, but some case reports and user surveys have described menstrual changes in women using Ozempic

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Therefore, microsphere sustained-release technology is being utilized to enable GLP-1 drugs to be released slowly and continuously, or GLP-1 molecules are being modified and optimized through structural modifications to develop GLP-1 RAs with longer half-lives
