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In vitro experiments have shown that GSH deficiency induced by either the siRNA approach or pharmacological inhibition of the GCL rate-limiting enzyme decreases GSH biosynthesis and escalates oxidative stress in cultured hepatocytes

Suitable solvents may include: Sterile water Buffered aqueous solutions DMSO (where applicable for in vitro systems) Storage Conditions Short-term: 28C Long-term: -20C or below Protect from: Moisture Heat Light Analytical Verification Each batch undergoes: HPLC purity verification Mass spectrometry identity confirmation Batch traceability documentation Research Applications NNMT Inhibition Research 5-Amino-1MQ is widely studied as a tool compound for evaluating NNMT activity in metabolic systems

GPX2 , Glutathione Peroxidase 2

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